Preimplantation genetic testing (PGT)

ABOUT PGT

A crucial tool

Preimplantation Genetic Testing (PGT) is an advanced reproductive technology designed to assess the genetic health of embryos created through in vitro fertilisation (IVF). It’s a crucial tool for couples undergoing fertility treatment, particularly those with a history of genetic disorders or recurrent pregnancy loss, as well as individuals of advanced maternal age. 

PGT enables the identification of chromosomal abnormalities and genetic mutations in embryos before they are transferred to the uterus, helping to increase the chances of a successful pregnancy and reduce the risk of genetic diseases in offspring. By using PGT, prospective parents can make informed decisions about embryo selection, ultimately enhancing their prospects of achieving a healthy pregnancy and welcoming a genetically normal baby.

What you can expect from us

Technical Excellence

Our experienced embryologists meticulously execute procedures with precision and safety, while our medical genetics specialists provide guidance to ensure adherence to the highest standards.

Cutting-Edge Techniques

Employing meticulous handling and top-notch biopsy methods, we prioritise preserving embryo viability, collaborating with world-renowned genetics laboratories to ensure an accurate diagnosis.

Patient First Ethos

Our philosophy emphasises patient autonomy, informed consent, shared decision-making, and personalised care.

WHAT TO EXPECT

Stages of treatment

In vitro fertilisation

We collect eggs from the woman’s ovaries and combine them with sperm, either from her partner or a sperm donor, in the laboratory to form embryos. For further details, explore our IVF treatment page.

Embryo Development

Once the eggs have successfully fertilised, they progress into embryos. Our team of embryologists employs cutting-edge methods like time-lapse technology, specialised equipment such as the EmbryoScope® to carefully monitor and evaluate their development. These advanced tools enable continuous, non-invasive observation, assessing various aspects such as cell division timing, cleavage regularity, and fragmentation within embryos. By scrutinising these factors, we can pinpoint the most promising blastocysts (day 5/6 embryos) for PGT testing, as they have a higher likelihood of being chromosomally normal.

Embryo biopsy

On day 5 or 6 of embryo development, a few cells are delicately extracted from each embryo for genetic testing. At this stage, the embryo comprises over one hundred cells. The biopsy process is minimally invasive, designed to cause minimal harm to the embryo. Using micro-manipulation techniques aided by laser technology, specific cells are carefully selected and removed. Following the biopsy, embryos are promptly vitrified for preservation.

Genetic Analysis

The genetic material collected during the biopsy undergoes analysis to identify potential chromosomal abnormalities or specific genetic mutations.

Selection and Transfer

Led by the genetic analysis, we select only those embryos free of chromosomal abnormalities or specific genetic mutations for transfer into the woman’s uterus. The placement of these embryos is typically confirmed using ultrasound guidance.

Pregnancy Test

After two weeks, you can take a pregnancy test, which can be conducted at the clinic through a blood test.

Embryo Freezing

Unused viable surplus embryos from the fresh treatment will be stored in our cryo-storage facilities. These preserved embryos will be available for future use in a subsequent frozen embryo transfer cycle, either for a second child or in case the first attempt is unsuccessful.

Learn more about how we can help

Arrange a free call with one of our expert Care Advisors today and learn more about how we can help you to achieve your dream of a family.